Help with Sleep
#21
(01-05-2017, 06:10 PM)ChasingGoodandEvil Wrote:
(01-05-2017, 06:07 PM)VoS Wrote:
(01-05-2017, 04:50 PM)James_001 Wrote:
(01-05-2017, 12:42 PM)VoS Wrote:
(01-03-2017, 10:43 AM)James_001 Wrote: Im desperate to sleep.

I wake up every night around four am and have trouble falling back asleep.

This all started with a traumatic incident years ago.

I've tried everything and nothing has helped for many years. I'm on twenty five mcg of cynomel a day in addition to the standard ray peat foods. My pulse and temps are good a lot of the time, yet I still can't sleep.

I'm going to try ketamine as I read it can help overcome trauma stored in the body. 

Insomnia, Suicide and the Redemptive Power of Ketamine

What do you think?
I use high dose urea therapy for sleeping. For me, I take about 15 grams of urea dissolved in a few ounces of syrup and soda or juice. If I do wake up after about three or four hours of sleep, as I often do, I take another 15 grams of urea.

I think if I were having trouble sleeping ever after taking the first dose, then I would take 15 grams of urea a second time. Typically, in clinics, urea is administered in two doses of 15 grams each.

I think the inability to sleep results from an excess of stress-induced anti-diuretic hormones. The excess of the stress-induced hormones then leads to an imbalance of sodium and other osmolytes, which is called "euvolemic hyponatremia" This means there is normal fluid volume (euvolemic) but too little sodium and other osmolytes in the fluid (hyponatremia).

Ray Peat often recommends sugar and salt to help with sleep. This may be helpful, too. Sugar and salt are also known to help with an excess of anti-diuretic hormones. 

But high dose urea therapy is known to be more effective and safer than sugar or salt to protect against an excess of stress-induced anti-diuretic hormones.
http://www.mdpi.com/2077-0383/3/3/1043/pdf

I have not used ketamine. It may be unnecessary if the high dose urea therapy works.

Where do you get urea from?

I defiantly have high stress hormones, I feel my adrenaline all day long.

I look for USP grade Urea. There are some here:
http://www.makingcosmetics.com/Urea_p_165.html\
https://www.amazon.com/Urea-UltraPure-Gr...00I31U9P4/
https://www.amazon.com/bioWORLD-42100008...01F7N4VUY/

Just to reiterate VOS, you say commercial grade urea is ok so long as it's 99+% pure? The urea i hve comes in tiny spheres, i'm not sure what import that has on its purity.

USP Grade is certified to be 99.8% pure, while commercial grade is 99+%. I think they are both safe. I use USP grade, since the price is not much more. 

The impurities mostly come from unconsummated reactants such as ammonia, ammonium carbamate, carbon dioxide and the water used. 

Yes, urea is made in granules that look like spheres. The granules can be crushed into powder if needed. 
My avatar: William Blake, Vision of Strength
[img]http://i.imgur.com/7sD2Hod.jpg[/img]
#22
(01-05-2017, 06:29 PM)VoS Wrote:
(01-05-2017, 06:10 PM)ChasingGoodandEvil Wrote:
(01-05-2017, 06:07 PM)VoS Wrote:
(01-05-2017, 04:50 PM)James_001 Wrote:
(01-05-2017, 12:42 PM)VoS Wrote: I use high dose urea therapy for sleeping. For me, I take about 15 grams of urea dissolved in a few ounces of syrup and soda or juice. If I do wake up after about three or four hours of sleep, as I often do, I take another 15 grams of urea.

I think if I were having trouble sleeping ever after taking the first dose, then I would take 15 grams of urea a second time. Typically, in clinics, urea is administered in two doses of 15 grams each.

I think the inability to sleep results from an excess of stress-induced anti-diuretic hormones. The excess of the stress-induced hormones then leads to an imbalance of sodium and other osmolytes, which is called "euvolemic hyponatremia" This means there is normal fluid volume (euvolemic) but too little sodium and other osmolytes in the fluid (hyponatremia).

Ray Peat often recommends sugar and salt to help with sleep. This may be helpful, too. Sugar and salt are also known to help with an excess of anti-diuretic hormones. 

But high dose urea therapy is known to be more effective and safer than sugar or salt to protect against an excess of stress-induced anti-diuretic hormones.
http://www.mdpi.com/2077-0383/3/3/1043/pdf

I have not used ketamine. It may be unnecessary if the high dose urea therapy works.

Where do you get urea from?

I defiantly have high stress hormones, I feel my adrenaline all day long.

I look for USP grade Urea. There are some here:
http://www.makingcosmetics.com/Urea_p_165.html\
https://www.amazon.com/Urea-UltraPure-Gr...00I31U9P4/
https://www.amazon.com/bioWORLD-42100008...01F7N4VUY/

Just to reiterate VOS, you say commercial grade urea is ok so long as it's 99+% pure? The urea i hve comes in tiny spheres, i'm not sure what import that has on its purity.

USP Grade is certified to be 99.8% pure, while commercial grade is 99+%. I think they are both safe. I use USP grade, since the price is not much more. 

The impurities mostly come from unconsummated reactants such as ammonia, ammonium carbamate, carbon dioxide and the water used. 

Yes, urea is made in granules that look like spheres. The granules can be crushed into powder if needed. 
Thanks.
[color=#222222][size=medium]"I have no religion, no political affiliation: I believe in me, above everything else." -Chasing Good & Evil[/size][/color]
#23
@vos what do you think of dht cream?
#24
(01-10-2017, 01:23 PM)James_001 Wrote: @vos what do you think of dht cream?

I avoid testosterone, dht and other male steroids. 

I think male steroids can be stressful, similar to estrogen or adrenal responses, unless the body is very healthy, and well supplied with glucose and insulin. The testosterone induced competition for sexual opportunities can be very high stakes, whether real or imagined. 

The largest increase in longevity ever discovered is the castration of Korean court eunuchs, who lived on average 20 years longer than non-castrated courtiers. 

One "male" steroid I do sometimes use is synthetic TUDCA. It's safe and and it seems to act the same way that pregnenolone does. In ancient Asian medicine, it was taken from the bile of the Asiatic bear.
My avatar: William Blake, Vision of Strength
[img]http://i.imgur.com/7sD2Hod.jpg[/img]
#25
(01-03-2017, 08:33 PM)James_001 Wrote: Yes I think I have a histamine problem because having an orgasm makes everything worse for me. 

What would you suggest instead of shrimp?

I feel like I am allergic to everything.

I hate cypro, and got into a car crash when I was on it. It makes me feel so dreamy/absent minded.

I have found fresh beef,lamb and chicken breast are easily digested.
Adding gelatin helps to balance the muscle meat, but gelatin can 
cause digestive problem for some. I used to feel hypo if i ate
muscle meat without enough calcium . Now i add extra calcium
whenever i eat muscle meat and do not get the hypo problem.
Amount of calcium should be higher than the phosphorus in muscle meat.
You can try egg shell power, if this causes problem then oyster shell
calcium is an option. I use oyster shell calcium as i find egg shell powder bit
allergenic. I think main focus should be eating tasty foods that does not
cause digestive or allergy problem. Farmer's cheese or greek yogurt
can be good source of protein. You will have to add some calcium with this.
A good part of calcium is drained from farmer's cheese and strained yogurt.
Dairy protein can cause constipation in some.

How much cyproheptadine you tried? I started with one fourth mg once
a day then slowly increased to 1 mg over a month. Even 1/4th mg caused
minor drowsiness for few days. Now i do not feel any kind of drowsiness
with half to 1 mg twice a day.

I have tried all 3 antibiotic fiber RP recommends and i found cooked
bamboo shoots to be most helpful. I use bamboo shoots from can
and cut into small pieces and then boil for 20 min and then wash it with
more water to remove the bitter taste. 100 grams of this 2-3 hours before sunset
quickly improve thyroid function and sleep. You can try grated carrot salad
too. You may have to add smaller amount of this fiber slowly depending
on your digestive power. In the beginning large amount these fiber can cause
bloating. 

Vitamin D 4000 iu, 100 mg of niacinamide 2-3 times a day, vitamin E 200 Iu
daily have been quite helpful in improving metabolism. It is good idea
to start with 50 mg of niacinamide to let body adjust to decreased
free fatty acids. You will need more carb to compensate for decreased
FFA and maintain blood sugar level. Niacinamide can improve liver
function by protecting liver from PUFA damage.
#26
(01-04-2017, 01:41 PM)VoS Wrote: Mittir, hi!

I see some mention in Ray Peat's work leads me to think that MCT emulsified in egg yolk could suppress the release of histamine. As less histamines are released, then there might be less of a histamine response possibly. 

Have you tried MCT emulsified in egg yolk? 
I have not tried MCT and egg yolk mix. I try to stick to
natural foods as much as possible. I make my own
coconut oil and i found it quite helpful. I also avoid
egg yolk for it's PUFA content and i think i get all
the nutrient found in egg yolk in beef liver.


I know MCT/Coconut oil prevents histamine release.
It is worth experimenting. But, RP's experience was not
that pleasant. He smelled like goat after taking small
amount of MCT oil. I wonder if MCT emulsified in egg
yolk would resolve that problem.
#27
(01-10-2017, 06:45 PM)Mittir Wrote:
(01-03-2017, 08:33 PM)James_001 Wrote: Yes I think I have a histamine problem because having an orgasm makes everything worse for me. 

What would you suggest instead of shrimp?

I feel like I am allergic to everything.

I hate cypro, and got into a car crash when I was on it. It makes me feel so dreamy/absent minded.

I have found fresh beef,lamb and chicken breast are easily digested.
Adding gelatin helps to balance the muscle meat, but gelatin can 
cause digestive problem for some. I used to feel hypo if i ate
muscle meat without enough calcium . Now i add extra calcium
whenever i eat muscle meat and do not get the hypo problem.
Amount of calcium should be higher than the phosphorus in muscle meat.
You can try egg shell power, if this causes problem then oyster shell
calcium is an option. I use oyster shell calcium as i find egg shell powder bit
allergenic. I think main focus should be eating tasty foods that does not
cause digestive or allergy problem. Farmer's cheese or greek yogurt
can be good source of protein. You will have to add some calcium with this.
A good part of calcium is drained from farmer's cheese and strained yogurt.
Dairy protein can cause constipation in some.

How much cyproheptadine you tried? I started with one fourth mg once
a day then slowly increased to 1 mg over a month. Even 1/4th mg caused
minor drowsiness for few days. Now i do not feel any kind of drowsiness
with half to 1 mg twice a day.

I have tried all 3 antibiotic fiber RP recommends and i found cooked
bamboo shoots to be most helpful. I use bamboo shoots from can
and cut into small pieces and then boil for 20 min and then wash it with
more water to remove the bitter taste. 100 grams of this 2-3 hours before sunset
quickly improve thyroid function and sleep. You can try grated carrot salad
too. You may have to add smaller amount of this fiber slowly depending
on your digestive power. In the beginning large amount these fiber can cause
bloating. 

Vitamin D 4000 iu, 100 mg of niacinamide 2-3 times a day, vitamin E 200 Iu
daily have been quite helpful in improving metabolism. It is good idea
to start with 50 mg of niacinamide to let body adjust to decreased
free fatty acids. You will need more carb to compensate for decreased
FFA and maintain blood sugar level. Niacinamide can improve liver
function by protecting liver from PUFA damage.
Thanks, I'll try some of this out. Honestly I think masturbation is the biggest thing ruining my health at this point...
#28
HOLY SHIT, I FEEL LIKE I AM GOING INSANE, WILL THIS EVER END!!!???
#29
In case anyone cares, I am making progress with a higher fat diet - 45% carbs, 30% fat, 25% protein alongside carbon dioxide therapy.

I really think the higher fat is key for keeping my bloodsugar in check, Previously I was doing around 20% fat.
#30
YAY! That's great, James! I'm so glad you're making progress. Smile
"One regret, my dear world, that I am determined not to have when I am lying on my deathbed is that I did not kiss you enough." ~ Hafiz
  


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